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This argues for that the differences in agreements between studies are likely to be influenced by the number of patients with moderate or severe symptoms included in the study.
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The differences in agreement patterns when examining different biomarkers and different scoring methods and reviewing whole slides compared to TMA stress the need for validation studies focused on specific pathology tasks to eliminate sources of variability that might dilute findings.
First, we considered differences in agreement across two different statistical methods.
It is worth noting the differences in agreement between arousal and valence.
Furthermore, it should be taken into account that there are differences in agreement on the importance of various risk factors.
In the original publication, the authors discuss the differences in agreement between typing methods in the two populations.
Diagnostic differences in agreement were calculated using Chi-squared analyses.
Results are given in table 3. Differences in agreement are tested with Pearson Chi-square test.
Differences in agreement in weighted Kappa for the four scales were analysed.
Differences in agreement between these subgroups in weighted Kappa were compared.
Both studies found negligible differences in agreement between cases and controls.
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