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27 However, this analysis reported that the ALS patients enrolled within the clinical trials were demographically and clinically different from the patients within the national ALS population, with the differences between the trial cohorts and patient population resulting in part from the different eligibility criteria used and in part from factors unrelated to enrolment criteria.
These differences between the trial and OBS groups were also reflected by the percentage of lymphocyte subsets.
There were no significant differences between the trial groups.
Table 3> -wrap-foot> provinformationabout about (relapse-free) survival differences between the trial arms.
We considered differences between the trial and BreathingSpace statistically significant if p < 0.05.
Results will be presented as mean differences between the trial groups, with 95% CIs.
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She and others said there were other differences between the trials that might explain the divergent outcomes.
The combined results from all trials (HR=0.65, 95% CI=0.53 0.80, P=0.0004) indicated a highly significant reduction in the risk of death with neoadjuvant chemotherapy, but there were some differences between the trials in their design and results.
Nevertheless, the limitations of pooled chi-square analyses have to be kept in mind especially for this comparison: using this method there is no adjusting for potential systematic differences between the trials using either DC type.
The Student's t test was used to detect differences between the trials at baseline.
All of these factors may explain the observed differences between the trials, including ours.
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