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Previous studies have identified distinct differences between the regulation of HKI and HKII [7], [8].
These interactions may explain reported differences between the regulation of PKG and PKA, such as the reversed order of the high and low affinity CNBDs and differences in cyclic nucleotide induced conformational changes, as revealed by small angle X-ray scattering [5], [31].
Differences between the regulation of clock genes in humans versus rodents have been observed.
The analysis exploits the subtle differences between the regulation of cell proliferation and nuclear size across 93 mutations.
It is interesting to note that yeast PDI is predominantly oxidised in vivo (Xiao et al, 2004), suggesting clear differences between the regulation of Ero1p and Ero1α in terms of their ability to be activated and to oxidise PDI.
Because there are evident differences between the regulation of mouse and human pluripotent ESCs (Hackett and Surani, 2014; Nichols and Smith, 2009) and during their early postimplantation development (de Fellici, 2013; De Miguel et al., 2010; Irie et al., 2014), this might affect the mechanism and the role of the key regulators of hPGCLC specification (Imamura et al., 2014; Pera, 2013).
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There is thus a fundamental difference between the regulation of gene expression in germ cells and soma, as perhaps there should be given the germline's connectivity of generations that span millennia, versus the soma's single generation relevance.
As previous studies reporting a direct interaction of CED-9 and CED-4 at mitochondria were performed in embryos, we reasoned that our results could be explained by the existence of a fundamental difference between the regulation of developmental apoptosis and germ cell apoptosis.
One of the main differences between the regulations of the oxidative stress responses in A. nidulans and S. pombe is that the number of genes likely under AtfA control was more stress-type-dependent in A. nidulans than in S. pombe (Table 5).
Thus, the goal of this study was to investigate the link between sex differences and the regulation of intestinal inflammation by analyzing jejunal biopsies and peripheral blood samples from healthy age-matched male and female participants.
Differences in the regulation of secretion between the different cell types with reduced/absent levels of REP-1 could explain the tissue specific degeneration that occurs in choroideremia.
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