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Due to the low thermal conductivity of polymers and the high thermal mass of commercially available compression platens, significant problems arise; large differences between the prescribed and polymer temperature, temperature variation through the sample and a slow temperature response are observed.
Baseline socio-demographic, psychiatric history and clinical data were collected to characterize the patient sample and detect initial differences between the prescribed therapies.
A previous clinical trial, including a multinational observational study by Vesconi et al. [ 19], also showed a wide variability in ultrafiltration rates with large differences between the prescribed and delivered doses, which was mainly due to circuit down-time [ 14, 20- 22].
Complex pathways such as complement and coagulation identified in the in vitro data set were not discovered in the analysis of the in vivo data set, which may be due to differences between the prescribed dose and actual exposure in liver tissue in vivo.
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The difference between the prescribed and actual depths are within the repeatability of the nanopositioning stage.
Then, the difference between the prescribed dose and the calculated dose was determined.
The difference between the prescribed amount and the tube feeding actually administered was expressed as a percentage and its associated 95% confidence interval (95% CI).
The patient can oppose substitution and retain a more expensive product, given that he or she pays the price difference between the prescribed and cheapest (reimbursed) product out of pocket.
Moreover, in those RCTs that have provided micronutrients as part of PN, such as SIGNET [ 17], which supplemented PN selenium, a difference between the prescribed and the provided dose is possible due to PN intolerance, which adds uncertainty about the true selenium daily dose.
However, we cannot exclude that this reflected unmeasured or unknown clinical or mechanical factors occurring during CRRT (for example, an undetected machine error at the time of sampling or a difference between the prescribed and delivered effluent flow rate); however, this also reflects clinical reality.
Similar results were obtained with propensity scores as an alternative method to adjust for differences between those prescribed and not prescribed β blockers.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com