The reported survival differences between the BI and some other European regions are small in absolute terms.
The differences between the BI and South (which had the highest survival of any European region for rhabdomyosarcoma) were similar for rhabdomyosarcoma and for all soft tissue sarcomas.
The verification of difference between the BI-only reconstructed maps and the actual maps (performed on the same 10 control LGs) showed a deviation of 2 cM at most for the entire mapping distance, and the markers always remained in the same order.
In the Bayesian tree (not shown) these nodes were collapsed, and were the only difference between the BI and ML phylograms.
On the other hand, by using single base resolution methylation data [ 33], we also analyzed methylation differences between the CGIs overlapping bi-directional promoters.
In spite of the differences between the ML and BI topologies and the weak statistical support of deep nodes in both analyses, we are able to draw some conclusions about the evolution of the DSL family.
Finally, a significant difference between the AECA BI of both groups versus normal donors was observed (P < 0.0001).
A significant difference between the AECA BI of group A and group B of SLE patients versus SSc patients was observed (P = 0.0002 and P = 0.01 respectively) (Fig. 1).
Differences were seen between the BI and the region(s) with highest 5-year survival for sympathetic nervous system tumours, renal tumours and soft tissue sarcomas (Pastore et al, 2006a, 2006b; Spix et al, 2006).
Although both TTM and PT programs increased the BI score by the conclusion of the study, there was no difference in the BI score between the two groups.
