When a nucleotide difference is in isolation, meaning that in neither ORF is there another difference in the same codon as the focal difference, the classification is straightforward.
The implicit numerical scheme that we have investigated is based on finite difference approximations and is straightforward to implement.
The difference is surprisingly straightforward: these neurons are simply wired up in different ways, routing the signal in one direction or the other within the fruitfly brain, rather like railway points in different orientations.
NHST is also preferable to AIC in the case of randomized experiments (Mazerolle 2006), where the null hypothesis of no difference is a straightforward baseline statement for framing analysis.
However, the functional implication of this difference is not straightforward because the RNA-recognition motif of the Dazl protein is located 30 amino acids downstream and is not affected, unless induced by configuration change.
Although PLAB graduates and UK graduates do not show outcome equivalence, interpreting and explaining that difference is not straightforward, and a number of possible moderating factors need to be considered.
However, extending the method to allow alternative measures of treatment effect, such as risk differences or relative risks, is straightforward and our spreadsheet also estimates these two measures.
Once the discrete transfer function of the controller is derived, its implementation in the form of a discrete recursive difference equation in the time domain is straightforward.
The method is straightforward.
