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No significant difference in the replicating viral numbers in the heart was observed between IL-6KO and wt mice at day 5 PI (Figure 1d).
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This may be due to significant differences in the replicate results of mRNA levels within individual patients.
No differences in the replicate spectra of this study were observed and thus only the first spectrum of each sample was used for analysis.
This is apparently due to the major difference in the number of replicates.
Similarly, any putative technical or biological problem associated to this study was resolved by using two complementary types of controls: First, using both biological and technical replication and showing differences in the biological replicates despite of the detected technical noise.
The differences found are attributed to the difference in selection pressures, the replicate population and the interaction between these two factors.
The finding of an absence of group difference in the control condition was replicated with preschool children [ 82]; but see [ 83].
However, in combining all replicates, the difference in the number of glycosylation sites that were identified in each replicate reflects an important advantage with regard to the number of unique identifications; thus, our experiments enhanced the coverage of the N-glycoproteome as much as possible.
This protocol outperforms an alternative quantification using the difference in the number of endpoint PCR replicates with positive detections, even in samples with low DNA presence37.
Northern extreme of India (Jammu and Kashmir) show major differences in replicating the spell characteristics.
Because of this variability, detection of a significant difference in the function of NAF and CAF required many replicates and multiple fibroblast cultures derived from different individuals.
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