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There was no difference in the outgrowth potential of the SP vs. NSP cells when 5,000 cells per fat pad were transplanted.
The results showed that there was no difference in the outgrowth potential of SP vs. NSP cells derived from the CDβ parental cells (Additional file 1).
The data on tumor outgrowth kinetics were pooled for two experiments, yielding a highly significant difference in the outgrowth ability of sFRP1-expressing cells (P < 0.0001, two-way RM ANOVA).
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We did not observe any significant differences in the outgrowth of vHMEC in cultures supplemented with conditioned medium from irradiated or unirradiated cultures (data not shown).
In adult animals, the difference in neurite length observed between wild type and daf-18 mutants was about half, consistent with the difference in the embryonic outgrowth rate.
Interestingly, when assessing also for rudimentary outgrowths (≥ 3% of fat pad filled), no significant difference in the number of outgrowths was observed between parous and virgin donors (Table 2B).
The difference in the relative length of outgrowth between young and very old fish was already significant at 3 days post amputation (dpa) and increased with time (Fig. 2B).
On slow NGF, or on slow Sema3A there was no difference in the directional specificity of axonal outgrowth.
From 9 dpa onwards, the difference in outgrowth was significant between all age groups.
No difference in SMPC outgrowth was observed between diabetic patients with and without MVD (Fig. 5d).
Because of the early difference in outgrowth kinetics (from 3 dpa onwards), we hypothesized that early events are crucial for the age-related differences in regenerative potential.
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