The authors of the study say it could be explained by an as-yet unidentified biological factor such as cancers in women of African-Caribbean descent responding less well to treatments, including hormone therapy or differences in the genetics of their tumours.
Over multiple environments, alfalfa genotype 773 consistently showed higher cell wall lignin content in stems compared to genotype 708 suggesting differences in the genetics of lignin biosynthesis.
Some investigators advocate that differences in the genetics of CYP will lead to personalized drug treatments, with a special emphasis on the geriatric population.
Whilst this may in part be due to differences in the genetics of hypertension between animals and humans it also illustrates the general challenges we are facing in candidate gene studies of human essential hypertension.
Significant differences in the genetics and biology of BC in Hispanics, including a higher incidence of TN BCs [ 25– 27] have been described as a significant contributor to their higher mortality [ 27].
Thus, there are fundamental differences in the genetics, biology and pathology of human germ cell development, compared with model organisms, that merit studies of human germ cell development per se.
Finally, sex differences in the genetics of OA have been noted for multiple genes and joint sites [ 72- 74], and studies of sex differences in these genetic effects should dovetail with those using advanced imaging and biochemical biomarkers for maximal mechanistic insight.
Although these models are centered on life-history traits relating to maturation and growth, there are interesting differences in how the genetics of the inherited traits and the life histories are modeled.
The difference in the contribution of genetics is, however, small given the very large difference in transmission intensity.
The difference in the physiology and genetics between sexes can contribute tremendously to the disease prevalence, severity, and outcome.
