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The difference in the exposure maps is similar to the corresponding instrument map comparison shown in Figure 6.
This difference in the exposure to adaptation measures is statistically significant (χ2 = 14.659 with P < 0.001), showing the existence of a verified difference between the two parts of the study area.
There was no difference in the exposure to light after a patient was admitted to the ICU.
Despite the lower dose per kilogram body weight in obese subjects, there was no significant difference in the exposure of oseltamivir carboxylate between the obese and nonobese groups.
Second, there was no difference in the exposure of pounders versus scrubbers toward particular patches of Luehea that could provide differential experience between these two classes of foragers.
When using the PBPK model to estimate peak blood concentrations, we found a much larger range in exposures and a significant difference in the exposure rankings (Table 1).
Similar(45)
There was a difference in the exposure-adjusted incidence rate of thyroid neoplasms between groups, ie, 0.3 per 100 PY (incidence rate < 0.1%) in the exenatide group and 0 per 100 PY in the pooled comparator group (RD 0.3; 95% CI: 0.01 0.53, Figure 5).
A study of rilpivirine and tenofovir, a nucleoside reverse transcriptase inhibitor (NRTI), in 15 healthy volunteers did not show any significant difference in the exposures of both drugs.
Although the ORs from different study regions (when available) are similar, there are substantial differences in the exposure distributions even within countries.
A comparison of the results of this juvenile study with an extended one-generation reproductive toxicity study revealed that the juvenile study design may result in a higher sensitivity related to differences in the exposure design.
These differences in the exposure response patterns can be (tentatively) explained in terms of the mechanisms for handling copper (an essential metal for earthworms) and cadmium (a putative nonessential element).
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