This reflects another fundamental difference in the databases' goals: while TCDB aims to transfer the full functional apparatus of a protein to all other family members, Pfam establishes relationships between individual functional modules that may be found in proteins with different functions.
For ASSIA, CENTRAL and Science Citation Index, however, it was difficult to construct comparable search strategies because of differences in the database search interfaces.
The detailed analysis using the genomic DNA of both Kazusa and GT-S strains indicated that the detected 21 putative SNPs were, in fact, differences in the database sequence, but not real differences in the two genomes.
These observations can be explained by taking a closer look at the differences in the databases and their spoofing attack scenarios.
The remainder of the difference may result from interannual variability in visit rates and differences in the databases used for the respective analyses.
Cross species sequence comparisons indicated that on the whole the Tortula clusters were more closely related to those from Physcomitrella than Arabidopsis (complete genome BLASTx comparison) although because of the differences in the databases there were more high scoring matches to the Arabidopsis sequences.
Among these three groups, the first have no significant difference in the three databases, indicating that there is no increased rates of change in any particular functional gene category or pathway.
Student's t-test was used for analyzing differences between publisheddatasets in the database.
The present study revealed that a significant number of differences are present in the database sequence and the genome sequences of laboratory strains of the same 'species' Synechocystis sp. PCC 6803.
In some cases, differences in solubilities can be attributed to differences in the thermodynamic databases used but, due to generally incomplete documentation, both of such databases and the criteria for data selection, detailed analysis of the reason for such discrepancies is precluded.
