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In addition, there was no difference in the change over time based on whether hospitals were or weren't participating in the program.
Both groups decreased waist circumference, however there was no difference in the change over time between the intervention and control groups (P = 0.236).
In the present study, no anti-inflammatory effect of insulin was detected as none of the investigated inflammatory markers showed any difference in the change over time between study days.
In difference-in-differences analyses, the coefficient of the interaction term and its subsequent 95% confidence interval (CI) represent the difference in the change over time in the intervention group as compared to the change over time in the control group [ 27].
There was a significant difference in the change over time between intervention and control for daily vegetable consumption at 8 weeks (mean 24 g; 95 % CI: -0.9 to 49) and 20 weeks (mean 39 g; 95 % CI: 12 to 67) (P = 0.019), which equates to a difference of 0.3 to 0.5 of a serve.
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However, these differences in the change over time between intervention and control group were not significant.> Intervention participants reported weight loss at 8 weeks, with an adjusted mean difference of -1.4 kg (95 % CI: -2.5 to -0.3) compared to the change in control.
Abbreviations: HD, hemodialysis; NT, no treatment; G, glucose infusion; GI, glucose-insulin infusion; hsCRP, High-sensitivity CRP; IL-1β, interleukin-1β; IL-6, interleukin-6; TNF-α, tumor necrosis factor α. ap-value for comparison of differences in the change over time between no treatment (NT), glucose infusion (G), and glucose-insulin infusion (GI) study days.
Mean BG levels were comparable at baseline (NT: 5.3 ± 0.4; G: 5.1 ± 0.5; GI: 5.1 ± 0.4 mmol/L, p = 0.13), but a significant difference in the changes over time were observed between study days (p < 0.001).
It is the difference in differences, or the differences in the changes over time, that are subject to analysis.
None of the investigated biomarkers showed any differences in the changes over time between study days.
None of the investigated inflammatory biomarkers showed any differences in the changes over time between study days.
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