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Interestingly, leptin KO AL mice showed no statistically significant difference in fraction of high activity relative to the leptin KO CR group (Fig. 4B).
There was a statistically significant difference in fraction of outliers for FFC angle in favor of the SPPC group.
There was a statistically significant difference in fraction of outliers for both the LFC angle and the LTC angle, both in favor of the SPPC group.
The overestimation of both these parameters was due to the difference in fraction of males in the part of the data set where sex was observed for all individuals (37% males) and the part where information about sex was missing (83% males).
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This can be explained by a difference in fractions of immediate cases.
Thus while the difference in fractions of ancient genes is suggestive, we cannot currently conclude anything from this finding.
However, comparison between ATG and GTG triplets that function as start codons and those that are not translation start sites shows no significant difference in fractions of ATG/GTG triplets overlapping with extended RY patterns between the two groups (Supplementary Table S18).
We detected no differences in fraction of antagonistic QTL across trait types.
The molecular BC subtypes have repeatedly been shown to display different CNAs [ 36, 49, 50], and, lately, also differences in fractions of LOH and CNN-AI [ 10].
The differences in fractions of steatosis were analyzed by McNemar's Test for paired categorical data.
The difference between cluster 1 samples and the remaining normal samples could be due to differences in fractions of the cell types present in the biopsies.
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