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There was no significant difference in exercise duration or ejection fraction (EF) with AVNA relative to pharmacotherapy.
One year later the difference in exercise capacity remained (26.5 (3.3) vs. 11.8 (3.8) watts, P<0.001).
The primary efficacy end point is change in exercise treadmill time in the treated vs active control patients, with 90% power to detect a 60-second difference in exercise time between cell-treated (n = 200) and active control (n = 100) patients.
However, there was no significant difference in exercise performance [22].
Perhaps the difference in exercise intensities for the two sessions was not substantial enough to elicit significant differences, such as those found in the current study.
Lead researcher Professor Douglas Losordo said: "The net difference in exercise tolerance is highly clinically significant, particularly in a patient population that is severely limited by symptoms.
Similar(36)
There was no statistically significant difference in exercise-induced ischemia.
Despite major differences in exercise prescription and duration of different programs, the aerobic capacity was significantly improved.
Differences in physique were not driving differences in exercise behavior.
There was evidence of heat storage while stinger suits were worn during beach activities in the absence of any differences in exercise intensity or sweat rate.
Some differences in exercise efficacy were perhaps attributable to total training volume.
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