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Conservation for a protein among species of different evolutionary distances implies dramatic difference in constraints on protein function and should be taken into full account in functional prediction.
The difference in constraints between autosomes and X chromosome (| CA − Cx|) is particularly apparent in unpaired portions of tRNAs and is in accordance with theoretical predictions that Ne will have a large impact on evolution at independently evolving sites.
When repeated separately for tRNAs grouped in core and peripheral sets, the same analysis also supports our previous conjecture that effects of Ne on the difference in constraints between X chromosome and autosomes are large if selection is weak (table 2, B) but much smaller when selection on the tRNA molecule is overall strong (table 2, C).
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The chi-square test (χ2) was used to test for significant differences in constraints identified in the study areas, at p < 0.05.
Consistent differences in constraints on trait evolution in insects and plants may also play roles in determining the imbalance of armaments.
The ND6 gene, encoded on the L-strand, is omitted because of presumed differences in constraints (e.g., base composition) relative to genes encoded on the H-strand.
Strategies that consider possible gender differences in constraints on HIV vaccine acceptance and, in turn, "meet men and women where they are" psychologically, socially, and geographically should be developed.
It would appear likely that these differences in constraints encountered would alter hand rim propulsion biomechanics in ways that may impact on the overall training required to maximise performance as well as the injury risk to the upper extremities.
Different classes of organisms (e.g. prokaryotes, unicellular eukaryotes, and multicellular eukaryotes) as well as different genomes structures (e.g. codifying sequences, introns, and "junk" sequences) can present huge differences in constraints.
To test whether differences in constraints are observed between the X chromosome and autosomes, we divided the 277 orthologous tRNAs for the D. melanogaster/ D. yakuba pair according to their genomic location into 21 X-linked and 256 autosomal tRNAs and obtained selective constraints separately for these two sets.
On the basis of the differences in constraints between managed and non-managed care plans, we hypothesize that: 1) length of stay will be shorter for managed care patients 2) there will be less variation in length of stay for managed care patients Physicians decide on treatment strategies and timing of discharge, thereby determining length of stay.
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