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Further work on the model has shown that a slight difference in assumptions can produce completely different results.
That our predictions differ may be in part due to the difference in assumptions on vaccine efficacy: while we assume equal efficacy across all age groups, Medlock et al. [ 18] assume that vaccines offer lesser protection in the elderly population, the population with the highest case mortality rates.
Consider, for example, the difference in assumptions between Frank's model [ 5] and the models presented above.
In what follows, we discuss the difference in assumptions used by Trasande et al. and the U.S. EPA.
It appears that the primary reason is the difference in assumptions about the fraction of used products landfilled.
The difference in assumptions between Pashler's estimate and Cowan's is reflected after dropping redundant terms by dividing Cowan's estimate by the correct rejection rate.
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In other words, a 1% difference in assumption of what is considered clinically significant provides a study with a poor or a high power.
Different sequence-based alignment methods can also give very different results, due to differences in assumptions and statistical and algorithmic approaches.
As a result of these differences in assumptions, predictions differed in important ways: one model suggested that reduction of antibiotic use would be a comparatively poor intervention when endemic transmission is high and that resistant organisms could persist endemically even in the absence of input from admitted patients or antibiotic selection (60 ).
3, 4, 25, 26 The current study estimates of screening benefits appear to be somewhat smaller than noted by Ladabaum and Song 25 and larger than those from Edwards et al 3 and Yang et al. 4 This is likely due to different study designs or periods, and differences in assumptions regarding the effectiveness of colonoscopy screening.
Due to differences in assumptions, the same logs result in three completely different representations of the subsurface in terms of the connectivity of sandbodies.
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CEO of Professional Science Editing for Scientists @ prosciediting.com