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However, the numbers of ER receptors are reduced in males relative to females [ 18]; it is not known if a comparable difference in ARs also exists.
This might also explain the lack of a significant difference in ARS volume of distribution in pregnant and non-pregnant women after oral administration.
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Real-time RT-PCR also failed to demonstrate any difference in AR expression between GPRC6A null and wild-type mice (Fig. 3B).
The twins within each pair are in good agreement with each other and we found that there is no significant association between difference in AR and age P-value=0.648 P-value=0.648
Importantly, our survival analysis showed that obese children had approximately 50% higher risk of undergoing AR by age 4 ½ years than nonobese children while the difference in AR prevalence between obese and nonobese children at age 4 ½ years was 9%.
The difference in AR gene and protein (Fig. 3) expression in LNCaP-AI cells was also not in itself statistically significant, and these results are consistent with loss of AR signalling in both systems.
Although the AR percent cells positive was higher in tumors of women who failed (70% vs. 57.5% for nonfailures), the difference in AR staining percentage did not reach statistical significance.
Also, no difference in AR mRNA expression level could either be detected in the PIK3CA mutated group of MA tumors compared to the PIK3CA wild type counterpart (data not shown).
The difference in AR between the Gail and Chen models was due to the fact that the Chen model includes breast density and therefore the baseline risk is considerably lower.
No differences in ARs or microfluctuations were found between the two refractive groups at any spatial frequency.
Thus these differences in ARs of the two serotype 5 clones may explain the enhanced virulence of ST 289.
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