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The average difference in administering the two treatment halves was approximately 2 minutes.
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Although glucuronidation is considered a high-capacity pathway, one cannot rule out the possibility that the rat to human difference in half-life was affected by the difference in administered dose.
Also, it is difficult to predict radioiodine kinetics during therapy from prior diagnostic studies owing to the large difference in administered and measured activity and potential subsequent biological effects.
Because of the difference in administered volume (4 L versus 2 L) between the two methods (oesophageal intubation versus bottle-fed), it can only be concluded from this study that an appropriate use of an oesophageal tube to feed 4 L colostrum is a safe and reliable method for an adequate passive immune transfer in healthy newborn calves.
Although the participating centers followed the Surviving Sepsis Campaign guidelines, differences in administered therapies might have occurred.
The time allowed for ingestion was always fixed and thus it was the rate of administration that resulted in the differences in administered oral agent volumes.
Note that this procedure leads to a unit-less value in which differences in administered tracer activity or blood glucose levels between pre- and postoperative conditions or between patients are canceled out.
To evaluate the differences in administered in a lipid emulsion compared to amphotericin B (AmpoB) in dextrose 5%, for the treatment of Candida albicans infection.
The aim of the present study was to describe the present oxygenation targets applied in ICUs in The Netherlands, and to determine whether outcome of ICU patients was associated with differences in administered oxygen (FiO2) or achieved arterial PaO2.
The randomized groups were similar, but there was a difference in personnel administering AAI training in those participants nonrandomly allocated to EpiPen, due to a staffing change part-way through the trial, and improved asthma control in the nonrandomized group.
The route of administration also changed significantly: after implementation, more patients received medication p.o. (comparable with the difference in the administered acetaminophen).
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