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Moreover, only using biological replication can we test whether the difference between two samples with different treatment is stronger than what we expect to see between two samples that are replicates, and therefore, whether that difference can be attributed to the cold treatment.
We have determined that in pairs of samples taken from a single tumour at the same time using 14 g core-cut needles, the variability in Ki67 would require an approximately 50% difference between two samples for these to be deemed significantly different from one another with 95% confidence [ 5].
According to the Biology-Online.org biology dictionary (//www.biology-online.org/dictionary.asp), a hypothesis is "a proposal intended to explain certain facts or observations" and a null hypothesis is "the assumption that any observed difference between two samples of a statistical population is purely accidental and not due to systematic causes".
where ∥.∥ defined as the vector module representing the difference between two samples.
The crucial physical difference between two samples is found from the optical bandgap value.
The two-sided Wilcoxon signed rank test examines the null hypothesis that the median difference between two samples is zero, against the alternative hypothesis that it is not.
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The t distribution can also be used to construct confidence intervals for the true mean of a population (the first application) or for the difference between two sample means (the second application).
It is an appropriate test to judge the significance of difference between two sample means with unknown population variance.
Eight out of 36 water samples from the same wells sampled in 2006 and revisited in 2007 (SI Figure S5) showed >50% [Rn] difference between two sampling events.
It has also been argued that the difference between two sample means is a better estimate of effect difference than zero [ 9].
Student's t-tests (independent samples t-test) or a u-test were adopted to determine the difference between two sample means.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com