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Many experts agree with Newman, and two large studies of P.S.A. screening, published in The New England Journal of Medicine in 2009, came to the same conclusion: There was no difference between the screened and unscreened groups in overall deaths.
As there was a significant proportion of non-attenders, and those that did attend were younger and less deprived, the 'healthy volunteer' effect may also have contributed to the relative lack of difference between the screened and unscreened populations.
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There were minor differences between the screened and non-screened regions in pre-screening incidence (Table 1 and 3).
Differences between the study population and the West of Scotland will therefore reflect differences between the screened and non-screened women.
The other five trials were rejected on the grounds of perceived differences between the screened and unscreened groups at baseline.
In the present study, we have noted differences between the screened group and the unscreened controls regarding treatment (Table 3), which are possibly explained by our screening intervention.
There were no differences between the infants screened and not screened.
But perhaps that's one difference between the screen and the stage.
* The standard deviation of the difference between the screening value and the baseline value 14 days later is for persons whose screening value was 16 or higher.
The randomisation in the DLCST was successful since there was no statistically significant difference between the screen group and the control group in relation to socio-demographic characteristics and smoking habits.
We found no direct evidence of bias using available data, but acknowledge that there may be differences between the patients screened and those not screened which may change the prevalence estimates.
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