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Nor did we find any significant difference between the randomised groups when we used the TIMI definition of major bleeding.
The difference between the randomised groups in symptom severity at one week was not influenced by proximity to death.
Per protocol is the difference between the randomised groups using only participants who received their allocated GORD management adjusting for BMI, age, sex, and baseline score.
The absolute difference between the randomised groups in terms of the proportion meeting our physical activity threshold was about 15% so there is still a possibility that physical activity itself might have some benefits for depression.
The primary outcome of the study is the difference between the randomised groups on the number of young people with FEP referred to EIS during the study period, analysed on the basis of intention to treat.
48 49 For the head to head comparisons, where much smaller differences in blood pressure were observed, we calculated similar blood pressure weighted estimates per 1 mm Hg difference between the randomised groups.
Similar(51)
The adjusted mean difference between those randomised to art therapy and those randomised to activity groups on the global assessment of functioning scale was −1.1 (−4.0 to 1.8, P=0.47) and on the positive and negative syndrome scale was 3.1 (−0.7 to 6.9, P=0.11).
The adjusted mean difference between those randomised to art therapy and those randomised to standard care alone on the global assessment of functioning scale was −0.9 (95% confidence interval −3.8 to 2.1, P=0.57) and on the positive and negative syndrome scale was 0.7 (−3.1 to 4.6, P=0.71).
The differences between the group randomised to the then-test and that randomised to direct measurement of change were negligible.
Hunger [ "How hungry do you feel right now?", answered on a 7-point rating scale anchored at −3 = Very hungry, 0 = Neither hungry nor full, +3 = Very full] and BMI were measured to examine whether there were any differences between participants randomised to different conditions that might affect the ratings of the snack foods.
There were also differences between the study patients randomised to 'full-PCT' and non-study patients in the length of time on caseload and intensity of input from the PCT (Table 3).
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