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The only difference between the discovery statements of these nodes is that they register to different KauNet pipes to receive the correct connectivity information for their respective link to the bus.
This approach takes into consideration the limited ability of Affymetrix platform to precisely define variant breakpoints and the difference between the discovery and the validation platform probe length (25-mers versus ∼60).
The difference between estimates in the two subsets gives an estimate of the bias, but we can also use the difference between the discovery estimate and our combined estimate from the two subsets.
The gender difference between the discovery and replication sets may also explain why rs1667255 failed to reach statistical significance in the NHS replication samples, despite having adequate power to detect an association (i.e. 99% power to detect a SNP explaining 1.7% of the variation in serum retinol at P =0.05).
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Differences between the discovery and the replication sets included origin within Europe, baseline disease activity, time of evolution, seropositivity, erosions and smoking.
Another possibility is the difference in handling of samples between the discovery and down selection phase.
The difference between webpage entity discovery and entity recognition in text data is that the former could resort to the html tag to recognize the candidate entities, while the latter always needs a string segmentation algorithm and inevitably is more difficult and results in more errors.
Richard Blackwell provides a helpful discussion on the differences between Descartes' discovery of the cogito and Wolff's empirical argument for the soul in his article, "Christian Wolff's Doctrine of the Soul," pp. 339-354.
The #difference between #understanding a #discovery and an #invasion is history books.
The unsuccessful replication could be due to false-positive findings from the discovery analyses, or differences in how atopy was assessed between the discovery and replication cohorts.
But let's not forget the difference between the life-long dedication to evidentiary discovery, or the fashioning of a new narrative from a nuanced study of the facts, and a writer's ability to market that idea.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com