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We maintained male offspring in 15 ppt Instant Ocean without T. suecica, as males do not eat, and a prior experiment had shown no significant difference between life span in 100% T. suecica with daily transfer (5.6 ± 1.4 days) or Instant Ocean without daily transfer (5.2 ± 1.4 days).
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How CR mediates life span extension, however, differs between life span measurements.
Although the two species have similar lifespans, there are extensive differences between life spans across species within the genus [ 61], and genes associated with longevity were identified within our previous study [ 46].
We found no correlation between life spans of individual mothers and the life spans of their female offspring (data not shown).
Still, there was a substantial difference between the life spans of junior and senior civil servants.
Still, there was a substantial difference between the life spans of junior and senior employees.
There was no difference in life span between the transgenic mice and control lines.
The difference in life span between Mecp2-single null and Mbd2/Mecp2-double null animals was not seen in a previous report [26] in which mice were on a mixed genetic background, whereas the mice in the current study were on a C57Bl/6 background, indicating the existence of strain-specific modifiers of life span in Mecp2-null mice.
The data presented in this paper have confirmed earlier reports and show a clear statistically significant difference in life span between the two main types of CGD, although it is important to keep in mind that there have been individual AR-CGD patients with early and extremely severe expression of the disease.
The present study shows no difference in life span between persons with and without pseudoexfoliation in our cohort.
The inter-individual differences between the life spans within a group appear at least as important as the differences between the groups.
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