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For this step, CloudBurst uses a variation of the Landau Vishkin k-difference alignment algorithm (Landau et al., 1986), a dynamic programming algorithm for aligning two strings with at most k differences in O km) time where m is the minimum length of the two strings.
We define Impact as the normalized difference between Alignment and Alignment∗.
Furthermore, the dendrogram analysis of actinoporins' N-terminal sequence allows relating differences in alignment with differences in activity among the four toxins.
The difference in alignment assessment between anatomic and mechanical alignments may be caused by deformities of the femur and/or the tibia [ 18].
The comparison of the differences in alignments is not straightforward with large amounts of indels, as even the same differences can often produce different alignments with the same alignment score.
This is a reasonable explanation for the difference of alignment density between samples A and B in Fig. 2 and thus for the heating-enhanced DEP process.
Figure 3 illustrates the difference in alignment quality before and after non-rigid registration.
Despite the great difference in alignment lengths and the pronounced sequence saturation as shown by the Steel and Xia tests, most MSAs still yielded highly similar tree topologies.
As such, the measure is conceptually similar to deformation-based morphometry, as described by Ashburner et al. [33], with the difference that alignment occurs in spherical surface space and follows individual gyral and sulcal patterns [31].
The difference in alignment has an immediate impact on the observed needle directions.
On average, there is 1.9% difference in alignment quality between the mBed approach and the full distance matrix computation.
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