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The phrase "differed markedly" is correct and usable in written English.
You can use it when you want to describe a situation where two things or people are significantly different from one another. For example, you could say, "Their views on the issue differed markedly."
Exact(59)
However, the strength of these contributions differed markedly across the different outcomes investigated.
The acceptability of surveillance differed markedly between countries.
Some of Chase's loan practices differed markedly from those of local lenders.
In its treatment of travellers Scotland has always differed markedly from England.
The pelvis differed markedly from the normal saurischian design.
In this respect the northerners differed markedly from the peoples to the southwest of the Nile.
In its tone and emphasis, Mr. Steinbrück's diagnosis differed markedly from that offered on Wednesday night by President Bush in a prime-time speech.
Though he fired her, their highly visible fight -- both passed lie detector tests -- differed markedly from the discipline of the Daley City Hall.
The study protocols differed markedly.
Notably, land use patterns in riparian areas differed markedly.
However, forest structure and composition differed markedly between these scenarios.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com