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The Structure-Activity Landscape Index (SALI) [9] can detect compound pairs that are structurally very similar, but differ largely in their activity value.
Germany and Chile differ largely in their GDP, and the German solid waste management system is highly advanced compared with the Chilean one.
Several varieties have been described that differ largely in their microscopic characteristics.
In general, the topology of the tree revealed PPRV isolates from diverse geographical areas differ largely in their partial N gene sequence.
DBA/2J and C57BL/6J mice have been shown previously to differ largely in their susceptibility to H1N1 (PR8M) influenza A virus [ 9, 18].
These 100 clusters differ largely in their gene composition: 50 clusters display significant resemblance with the DMD+ cluster 1, while the 50 others contain significantly more genes observed in the DMD- cluster 5.
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The two relevant enzymes, ubiquinol cytochrome c oxidoreductase and cytochrome c oxidase, appear as rather diverse modules, differing largely in their design for substrate interaction, internal ET, and moreover, in their mechanisms of energy transduction.
Green points that differ largely in LE from their cluster seed are indicative of activity cliffs because small structural changes strongly affect the LE.
Our finding that PL was significantly associated with the Q matrix from STRUCTURE (Table 4) might be explained by the fact that farmers preferences seem to differ largely in different regions of WCA (cf. [ 27]).
These "synonymous mRNAs" may differ largely in a number of aspects related to their overall translational efficiency, such as secondary structure content and availability of the encoded transfer RNAs (tRNAs).
Different product families, however, may differ largely in terms of the number and nature of components.
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