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We hypothesized that 1) the two species would differ in concentrations of metals important in melanin synthesis (Ca, Fe, Cu, Zn), 2) differences in metal concentration levels would be related to feather coloration.
The 4 treatments, formulated to be isoenergetic and to differ in concentrations of dietary crude protein (CP) and starch (DM basis), were as follows: low CP and low starch (LPLS; 14% CP and 15% starch), low CP and high starch (LPHS; 14% CP and 25% starch), high CP and low starch (HPLS; 16% CP and 15% starch), and high CP and high starch (HPHS; 16% CP and 25% starch).
A regularized Hotelling T2 procedure was used to identify sets of proteins, defined by biological pathways, that differ in concentrations between cases and controls for each study disease.
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For instance, hormones modify taste receptor cell activity and differ in concentration among people.
Besides differing in number of serotypes, PVC10 and PCV13 differ in concentration of the capsular polysaccharides, the conjugation process, and carrier proteins, possibly leading to different immunogenicity and memory induction between these 2 vaccines [ 6].
All the preceding work was focused on the question: Are there any metabolites that differ in concentration levels between samples from the test population indicative of a specific pathophysiology?
Three riverine sediments (Zollelbe, Prossen, and Ehrenbreitstein) that had a similar distribution of particle size and physicochemical properties but differed in concentrations of DLCs and PAHs were used in exposures [23, 27].
In addition, H. wrightii specimens grown in environments with relatively small differences in salinity (35 and 38 ppt) contained sulfated polysaccharides that differed in concentration by almost 50%.
For comparative purposes, we also fabricated SERS substrates by depositing GNR sols differing in concentration directly on plain silicon wafers as described previously in [33].
Analysis of covariance (ANCOVA) using the General Linear Model (GLM) procedure in SAS was used to determine analytes that differed in concentration between AD and control groups while adjusting for the effects of age and gender.
We found that several of the dimers differed in concentration (KA, EQ) between the two proteins indicating that the dimers were capturing information discriminating between interacting and non-interacting proteins.
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