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Denominators differ from the incidence column due to missing survival status (17/562 patients).
The incidence of diabetes after therapy cessation with either of the agents evaluated did not differ from the incidence observed with placebo.
Of course, when the above steady-state assumptions are not met, which will frequently be the case, then both the POR and the prevalence ratio will differ from the incidence rate ratio (Thompson et al. 1998), and which measure is more "valid" will be highly specific to the population, exposure, and disease.
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From visual inspection, the reconstructed incidences do not differ from the true incidences.
The reconstructed incidences visually do not differ from the true incidences.
One point of caution is that our projected underlying incidence rates differ from the actual observed incidence rates in recent years.
Annual incidence rates in patients after several years of lithium treatment (1.4 1.8 %) (Bocchetta et al. 2007a) did not much differ from the ranges of incidence reported for the general population, with maximum values of approximately 2 % per year in women aged over 45 (Vanderpump et al. 1995; Tunbridge et al. 1981).
The arrows suggest that the A, C, and G incidences around the first nucleosome dyads and linkers downstream of nucleocyclic TSSs significantly differ from those incidences around nucleosomes in the entire genome in Figure S4d.
Briefly, this method allows for the fact that patients who die are no longer at risk for second cancers, so it differs from the cumulative incidence estimated by the Kaplan-Meier method, which treats competing events as censored at the time they occurred.
Another limitation is that we studied both cancer mortality and hospital admissions as proxies for cancer incidence thereby assuming that the mechanisms relating allergy to cancer incidence do not differ from the mechanisms relating allergy to cancer mortality or hospitalization.
In light of the above mentioned facts, it seems possible that the actual incidence rates of UI differ from the estimates reported by epidemiological studies.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com