Estimated exposure concentrations differ from the household concentrations because they account for proximity factors for cooks and small children and also account for some people not being home during all periods when indoor concentrations are elevated.
In individuals with certain pathological states, the MP levels differ from the baseline concentrations found in their healthy counterparts; the concentration of MPs could be either elevated or decreased (see Table 2).
A possible reason for the poor correlation between the clinical response to VGB and its concentration in serum or CSF is that these concentrations may differ from the VGB concentration in the brain ECF, which is the compartment to which the brain cells are directly exposed.
However, the total concentrations represent the sum of all compounds showing cross reactivity against striatal B. They may thus differ from the individual concentrations determined by HPLC.
Third, the sTREM level measured in BAL fluid is lower as a result of dilution and may differ from the actual concentrations in some patients, although we performed exactly the same technique and retrieved similar volumes in the three groups (data not shown).
"In Table 1 [BNID 110745], the values refer to the concentrations of the "free" ions, which may differ from the total concentration of the ion in plasma or cytoplasm.
This is particularly important when the drug concentration in different age groups may differ from the respective target concentrations, in which case the MM approximation may predict different AUC0 infinity, pediatrics/AUC0 infinity, adult compared to those obtained from the TMDD model.
Individual fetal blood concentrations did not differ from the corresponding maternal concentrations, indicating that measurement of maternal PBDE blood levels is useful in predicting fetal exposure; similarly, other reports have shown a high correlation between PBDE in mother's milk and fetal exposure.
Mutant genotypes differ from the wildtype in the concentrations of one or more constituent proteins of the chemotaxis signalling network or in one or more of its kinetic parameters.
As the time point of the highest concentration (Tmax) in simulations can differ from the reported Tmax, predicted and observed concentrations were compared at the in vivo Tmax.
