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Fluctuation from the PRC-repressed to the canonical active state (S5p+S7p+S2p+) occurs to variable extents across different PRC targets, resulting in differing expression levels.
Most likely, due to differing expression levels of the two genes in different cell types and tissues, endogenous ABCD2 cannot replace ABCD1 functionally (18, 19).
We also observed differing expression levels of APOE-001 and -002 splice variants in the AD temporal lobe.
Circulating miRNA expression patterns might therefore differ from expression patterns extracted from the diseased organ itself.
In total we identify 343 genes that differ in expression between the populations and 91 genes that differ in expression between the sexes.
Indeed, in the well-studied model organism Drosophila melanogaster, genes that differ in expression between the sexes (sex-biased genes) greatly outnumber those that differ in expression between individuals of the same sex [ 4- 6].
Here we ask a somewhat different but equally fundamental question of sequence that varies among genes with dissimilar expression: Are regulatory regions different for genes differing in expression, and similar for genes not differing in expression?
These molecules differ in expression level, location, pathological stimulation, and/or endocytic pathway.
Naïve and memory CD4 subsets differ by expression of CD62L and either CD45RO (memory) or CD45RA (naïve).
The fourth gene, CHKov1, did not differ in expression between populations in our gene-based analysis.
A set of genes encoding chemosensory receptors was found to differ in expression between the populations.
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