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Physical inactivity did not differ by parity group, contrary to other observations.
Age-adjusted ghrelin and leptin levels did not differ by parity category.
The authors did not explore whether other ovarian cancer risk factors differ by parity.
Family history of diabetes, exercise, insulin resistance, and leptin and ghrelin levels did not differ by parity group.
Recent studies have suggested that several ovarian cancer risk factors differ by parity status, but these findings have not been confirmed.
While nulliparous women have higher ovarian cancer risk than parous women, our findings suggest that the relative effects of most other risk factors do not differ by parity.
Similar(50)
Covariates included in the multivariable models consisted of variables that differed by parity group and those associated with diabetes in univariate analysis.
Low adiponectin was independently associated with type 2 diabetes in this analysis, and levels were significantly lower in multiparous women, but neither insulin resistance (by HOMA-IR) nor leptin concentration differed by parity group.
Absolute event rates were higher in nulliparous women but there was no evidence that the relative decrease in the risk of an adverse event ('main composite') in planned home births differed by parity.
In the present register-based study, comprising information for 22,867 Norwegian breast cancer cases 20-74 yearss), we examined whether histological type (9 categories) and grade of tumor (2 combined categories) differed by parity or age at first birth.
The aims of this study were to determine whether teenage pregnancy was associated with reduced infant birthweight and with increased rates of small for gestational age (SGA) and preterm birth, whether the association differed by parity, and whether any associations were independent of confounding factors.
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