When exposed to white noise, in contrast, headshaking and dusting were less frequent and rates did not differ across phases of the playback trials (Friedman's ANOVA, n = 13, headshaking: F = 0.55, p = 0.135; dusting: F = 1.19, p = 0.092; Figure 2a and 2b).
The consequences of sedentary behavior may differ across groups.
While these exploration times did not differ across the two Phases, F 1, 37) = 1.17, p =.29, the HpcC1 rats showed higher overall levels of object exploration, F 1, 37) = 21.4, p <.001.
The rate and types of adverse events were much the same across all groups (treatment and placebo) throughout the different phases of both studies, although absolute event rates differed across study phases consistent with different lengths of follow up.
Although our MTL novelty effects did not differ across the learning and replacement phases, we did observe that ventral pallidum and midbrain/VTA BOLD activity was higher during navigation in novel versus familiar environments during the replacement phase, while environmental novelty related activity in the caudate was higher during the learning phase.
ITIs were therefore variable (mean ± SD, 6.23 ± 0.07 s) but did not differ significantly across phases of each experiment.
Intertrial intervals were therefore variable (mean ± SD, 6.90 ± 0.79 s) but did not differ significantly across phases of each experiment.
Braak NFT stage differed across Thal amyloid phase (P < 0.001, chi-square), as shown by Fig. 2. A Braak NFT stage of <IV is consistent with NFTs restricted to limbic regions and not yet involving cortical regions (Braak and Braak, 1991).
Brain weight was higher and Braak NFT stage was lower in Thal amyloid Phase 3. The presence of TDP-43 and vascular disease did not differ across Alzheimer's disease cases in Thal amyloid Phases 3 5.
Second, grading standards differ across courses in different majors.
