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The methylated biosynthetic intermediates between lanosterol and 7-dehydrocholesterol in the K R pathway (i.e., dihydrolanosterol, dihydro-ff-MAS, and dihydro-t-MAS) did not turnover at comparable rates to either lanosterol or 7-dehydrocholesterol, suggesting that the classical K R pathway was not used to synthesize cholesterol in these cells.
Fluorescence recovery after photobleaching (FRAP) and inverse-FRAP experiments revealed that the Spn-F GFP at the diSpn-F GFPid not turnover within 3 min (Fig. 1B-E; supplementaty matheial Movies 1 andistalas distipct from GFP::Rab11, which turnedidver withinot0 s (Oturnoveral., 2011).
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Our data showed that three species of medical importance were common across the sampling locations: Lutzomyia gomezi, Lutzomyia panamensis and Lutzomyia evansi, suporting that vector species do not turnover in the studied setting.
By 14dpi (days post-irradiation), cells around the anterior have disappeared, suggesting that these cells do not turnover as quickly as zpuf-6 + epidermal cells.
Our recent results suggest that these multi-protein transport channels do not turnover in post-mitotic cells, where the mitotic renewal of NPCs is absent.
After 14 days post-irradiation, NB.22.1E and laminB mesenchyme expression is completely lost, but only cells in the anterior region have disappeared, indicating that the marginal edge cells do not turnover as quickly.
We wondered whether there was minimal co-expression between zpuf-6 and NB.22.1E and laminB because these marginal adhesive cells do not turnover as quickly as epidermal cells on the dorsal and ventral surface.
One encouraging fact may be that inflammatory macrophages and monocytes do not turnover as fast as their normal counterparts, and these cells may maintain their FR expression in time to allow for FR-specific intervention.
By contrast, salary and bonus -- which now combine for less than a third of executive pay at big companies -- did not affect turnover, the Texas researchers found.
Clinician demographic, professional background, and perceptions of the treatment model and demands did not predict turnover.
We found that the knockdown of ACTN4 did not affect turnover of focal adhesion (data not shown).
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