Sentence examples for did not substantially impact from inspiring English sources

In particular, targeted mutation of genes encoding several potential membrane proteins that can associate with SHP1, including those of CD72 and CD22, did not substantially impact the development of B1 B cell lineage [9], [10], [11], [12].

Correcting for the median or mean (by using the coefficient of variation) did not substantially impact our results, because all "typical" QTL even extremely weak ones (nominal p = 0.01)—were already excluded from the analysis.

Sample type (deep throat swab or sputum) explained only 7% of community variance (p = 0.001), with age group explaining 33% (p = 0.001), suggesting that the method of sample collection did not substantially impact community compositional differences, although differences in the site of sample collection likely explains this low level of variance observed.

Importantly, multiple labs have found that the lack of either IL-21 alone [24], [25], [26], [27] or IL-6 alone [27], [28] did not substantially impact development of Tfh in vivo in the context of protein immunizations or viral infections.

Interestingly, risk perception variables did not substantially impact protective behaviours.

The majority of one-way sensitivity analyses did not substantially impact the ICERs compared to the base case analyses.

Bickerstaff et al. [3] argue thatpromoting public involvement and participation does not substantially impact local transport policies, because participants'comments are not incorporatedinto local transport plans or other documents.

Several limitations to this manuscript are noted, although they do not substantially impact the enthusiasm for the findings.

Empirically, substituting sample-specific templates for the reference templates in the current data set does not substantially impact any of the reported relationships to cognition.

However, the study's population coverage was still reasonably broad and it has been shown that the sample profile does not substantially impact on associations within the data.

It is perhaps somewhat surprising to find that patients whose tinnitus does not substantially impact on their quality of life appeared to be the ones most often seeking help.