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Adjustment for FAs, which are considered established diabetes risk markers, did not substantially attenuate this association.
The addition of this variable did not substantially attenuate any of the significant associations from Model 2, with the exception of women's education, which dropped to marginal significance.
However, adjustment for magnesium intake did not substantially attenuate the inverse association (4, 5), suggesting that other bioactive compounds in coffee may also be responsible.
In both cases, adjustment for hypothesised confounders did not substantially attenuate the relationship when compared with unadjusted or age adjusted models.
Also, adjustment for a large number of covariates via a regression model weighted for a propensity score did not substantially attenuate this finding (2.25, 1.11 to 4.54, P=0.024).
Adding covariates that may be on the causal pathway linking air pollution with atherosclerosis, such as blood pressure or medication to control blood pressure, did not substantially attenuate the coefficients.
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Additional adjustment for light intensity activity during the same time period did not substantially alter risk estimates (RR: 0.85, 95%CI:0.76,0.95), and adjustment for current BMI slightly attenuated but did not abolish the multivariate association (RR:0.87, 95%CI:0.78,0.95).
Further adjustment for home ownership and poverty did not substantially alter these results, but adjustment for population density and metropolitan area population attenuated the segregation effects, suggesting a mediating or confounding role.
The results of our sensitivity analysis indicated that associations of PM10, and NO2 with depression symptoms in two-pollutant models were attenuated, compared with single-pollutant models; however, controlling for other pollutants did not substantially change the risk estimates.
Knowledge of result did not substantially modify these effects.
Adjustment for smoking did not substantially change this estimate.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com