Lawson 20 highlights the need for more research to ensure that the correct infants are treated at the right time and that fashion does not dictate unnecessary interventions.
Understanding the patients' rationale for CAM therapy and their perception of its efficacy may provide information on whether symptoms or the illness dictate intervention and on positive or negative consequences of CAM therapy [ 23, 24].
A limitation is that it leaves unanswered the question of whether the apparent advantages of some treatment strategies were dictated by the intervention, or if it was the illness state the governed the choice of intervention.
The study designs to be included in a review should be dictated by the interventions and outcomes being considered.
While there is broad agreement that the study designs to be included in a review should be dictated by the interventions being reviewed, there is uncertainty regarding what study designs to include for some specific types of questions.
In the absence of explicit criteria, resources will always be allocated to interventions dictated by influential members of the decision making panels especially when power differences exist in the priority setting team.
This approach is consistent with other guidance for systematic reviews, such as those of the Cochrane Health Promotion and Public Health Task Force, which recommends that: "The study designs to be included in a public health review should be dictated by the interventions being reviewed (methodological appropriateness), and not vice versa" [ 9].
While a drop in hemoglobin concentration is an indication for prompt blood transfusion, hemodynamic deterioration dictates surgical intervention with subsequent hemostatis.
One solution here may be to adopt a non-randomised approach which capitalises on, rather than ignores, motivational differences between participants by allowing patient choice to dictate the intervention group rather than chance allocation.
This study aims to report the extent to which administration of platelets, fresh frozen plasma, and cryoprecipitate would be indicated using protocol-dictated interventions by the Rotem, TEG, and conventional coagulation screens during orthotopic liver transplantation (OLT).
Patients received treatment with the DRX9000 (Axiom Worldwide, Tampa, FL) as dictated by the intervention's operating guidelines[ 11].
