This prompts the question of whether the tissue rather than the ontogenetic origin of the macrophage dictates functionality of these cells.
Our study's results also appear to differ from certain studies in mammals that have suggested that strength of TF binding corresponds with circadian phase-specific DNA binding (Rey et al., 2011) and possibly even dictates functionality (Rey et al., 2011; Whyte et al., 2013).
Quantitative measures of isometric [ 4, 9- 12] and isokinetic [ 4, 11- 23] strength have been described to dictate the functionality of muscles in different muscle actions.
It had never been shown whether the nonhematopoietic environment in which NK cells mature dictates their functionality.
Surface topography and refractive index profile dictate the deterministic functionality of a lens.
This is partially dictated by the functionality of each module.
These companies do not follow either of the design industry's norms: "tech push," whereby an improvement in performance and functionality dictates a modification in design, or "market pull," whereby the design accommodates consumers' demand for new features or an up-to-date look.
Alessi, the lighting manufacturers Flos and Artemide, the furniture maker Kartell, and a handful of other firms based in the Lombardy region ignore the design industry's two norms: "tech push," whereby an improvement in performance and functionality dictates a modification in design, and "market pull," whereby the design accommodates consumers' demand for new features.
Each of these tools relies primarily on the basic assumption that residue functionality dictates sequence conservation, which can consequently be used to infer deleteriousness.
This functionality dictates that these residue positions will be evolutionarily conserved, although some positions may allow a flexible subset of amino acids such as similarly sized hydrophobic side chains (e.g., Ile, Leu, Val) or side chains with similar charge (e.g., Asp, Glu) [ 38].
