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Finally, 77 potential participants were eliminated at the end of the run-in of optimised acute treatment on the basis of their diary recordings: 44 recorded 20 or more headache days per 30 days, and 33 did not meet the criteria for severity of migraine.
Further work is needed to determine the optimal recording timeframe for diary recordings, as adherence rates may decrease over time, thus reducing the validity of estimates.
Daily electronic diary recordings indicated high adherence; about 90% of participants recorded that they took their preventive drug on at least 25/30 days.
In diary recordings, 7.6% (n = 18) of the adolescents recorded no headache episodes during the 3-week recording period.
At the end of the 12-week intervention phase, objective lung function tests and patient-rated day and nighttime symptoms based on diary recordings showed little or no change.
The response rates in completion of questionnaires and diary recordings were also acceptable.
There is inconsistency in the estimates of headache characteristics between retrospective reports and diary recordings.
In that study, headache intensity was higher in questionnaires than in diary recordings.
The corresponding percentages as reflected by diary recordings were: 9%, 6.8%, 42.3% and 41.9%, respectively.
Three complete weeks of diary recordings were performed by 68.1% (n = 342) of the students.
The latter measure showed the highest and a positive correlation with number of headache days as reflected in diary recordings.
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