Sentence examples for diagnostic substrates from inspiring English sources

As one possible mechanism of antigenotoxicity, the inhibition of activating enzymes was studied either indirectly with diagnostic substrates or directly by measuring CYP1A2 inhibition.

Thus, lipid metabolites appear to be highly useful as diagnostic substrates for the diagnosis of AD and mild cognitive impairment (MCI) in plasma.

Since tissue culture and fixation protocols are considered a trade secret by manufacturers of HEp-2 diagnostic substrates, the reasons for this finding are not fully understood.

Using a targeted molecular approach, we identified putative allelochemical-responsive C. gibbosum CYP4 cDNAs, measured their transcript expression following allelochemical exposure, and assessed their ability to metabolize diagnostic substrates.

To enhance interpretation, we used diagnostic substrate to product metabolite ratios: the well-established THF+5α-THF/THE ratio and the cortol/cortolone ratio as a further confirmatory ratio.

The enzyme expressed maximum activity of 205 nmole/min/mg at pH 7.4 toward the diagnostic substrate TSO with an apparent Km of 1.7 microM.

Two forms of human liver cytosolic epoxide hydrolase (cEH) with diagnostic substrate specificity for trans-stilbene oxide (cEHTSO) and cis-stilbene oxide (cEHCSO) have been identified, and cEHCSO was purified to apparent homogeneity.

This phenotype profiling was performed using a "matrix" approach where 14 representative Shewanella species were profiled against a panel of 18 diagnostic sugar substrates (Table 3).

In this study we demonstrate that single amino acid substitutions can result in subtle changes in substrate preferences and supports the notion that the active site loop sequence can be used as diagnostic of substrate specificity.

Cleavage at a predicted location is diagnostic for substrate processing by Ago2 and we used 5′ rapid amplification of cDNA ends (5′ RACE) to further test whether silencing of RNA in the nucleoplasm and on chromatin was due to Ago2-mediated cleavage.

In this paper the recent results of neutron irradiation tests on diagnostic windows, bolometer substrates and magnetic coils at JAERI are described.