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Dual-contrast MRI with liver-specific agents should be used to improve diagnostic specificity for small lesions.
We selected the most specifically expressed gene, namely LIN28A, and subsequently tested its diagnostic specificity for ETMR with a high-quality commercial antibody on a large cohort (n = 816) of paraffin-embedded brain tumors.
In an attempt to improve diagnostic specificity for active TB, PPD reactive CD4 T cells were stratified according to their cytokine profile into populations secreting IFN-γ only, IL-2 only and dual-cytokine-secreting cells (figure 2).
Therefore, the NR had the highest diagnostic specificity for the diagnosis of AGA.
Increasing the cutoff limit increases the diagnostic specificity for RA, but decreases the sensitivity.
The apparent difference between these studies may relate to diagnostic specificity for CFS.
Similar(33)
CEA samples from human rather than recombinant proteins are essentially required to improve the diagnostic specificity of CEA for cancer detection in clinical application.
This rise in total number of requests as well as the increased number of inappropriate requests determines a drastic reduction in the pretest probability of disease and, as a result, calls for greater attention to the diagnostic specificity of the tests used for screening for anti-intracellular antigen autoantibodies [59].
When the control sera from the same sample set of donors were used, the numbers of true negatives and false positives were 15 and 4, respectively, suggesting a diagnostic specificity of 78.9% for determining whether ELISA reactivity is due to an exposure to anthrax toxin PA (Table).
To detect an improvement in diagnostic specificity from 50% (WHO algorithm for paediatric pneumonia) to 80% (CLSA and WHO algorithm) with 95% power and α of 0.05 between pneumonia and non-pneumonia cases, we require 70 patients per group in the training set.
The diagnostic specificities of the methods differed for most comparisons, with greater specificity for PET.
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