(DOC 28 KB) 13613_2012_107_MOESM2_ESM.doc Additional file 2: Diagnostic score for DIC according to the Japanese Association for Acute Medicine JAAMM).
However, recent studies have determined a more sensitive diagnostic score [15], which has been accepted by the scientific community [21].
To develop and validate a diagnostic score that assists in discriminating primary hemophagocytic lymphohistiocytosis (pHLH) from macrophage activation syndrome (MAS) related to systemic juvenile idiopathic arthritis.
The result of following the flowchart from the top to the bottom is a diagnostic score that reflects increasing probabilities of malignancy, ranging from 1 to 11.
Results To validate the diagnostic score, we collected data from an independent dataset of 238 patients with HMS admitted to 26 ICUs for ARF (iVNIctus trial), including 15 (6.3 %) patients with PjP.
Dupas et al. were the first to describe a diagnostic score based on a seven-point score [8], which Frampas et al. simplified to establish the current four-point reference score based on the lack of opacification of each ICV and C-MCA [15].
In conclusion, we provide here an original and reliable diagnostic score involving platelet count and serum creatinine level to predict severe acquired ADAMTS13 deficiency on diagnosis.
However, the relatively lower specificity indicates that additional clinical parameter(s)/serum biomarkers should be added for the formulation of an applicable diagnostic score for stomach cancer patients.
Serum levels of apoC-I and apoC-III combined with other clinical parameters can serve as a basis for the formulation of a diagnostic score for stomach cancer patients.
The original diagnostic score we established, based on the differences we identified between patients with ADAMTS13 deficiency and those with a detectable ADAMTS13 activity (≥20%) (ie, serum creatinine level, platelet count and, to a lesser extent, ANA positivity) may therefore rapidly identify patients with acquired, immune-mediated ADAMTS13 dysfunction.
A reliable diagnostic score integrating different parameters is lacking [ 8].
