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The essential difference between the two studies was that in the first family physicians were asked to note all the diagnoses of the participants, which included depression and/or anxiety, and in the second study diagnoses of depression and anxiety disorders were ascertained using standardised diagnostic interviews by research interviewers.
Research diagnoses of ADHD and psychiatric comorbidities were ascertained using the parent version of the Child and Adolescent Psychiatric Assessment (CAPA) [ 35], a semi-structured interview.
Hospitalizations were ascertained using the Canadian Institute of Health Information CIHII) Discharge Abstract database, which contains detailed information on diagnoses and procedures for admissions to all acute care hospitals [ 24].
Dilutions were ascertained using UV measurement.
Complications were ascertained using standard criteria (24).
Macrovascular complications were ascertained using standard procedures.
Cardiovascular complications were ascertained using standard procedures.
In PREDICT-D mental disorders were ascertained using standardised questionnaires.
Other chronic complications were ascertained using standard criteria.
Hemoglobin (Hb) levels within children were ascertained using HemoCue.
Differences between group means were ascertained using Tukey's test.
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