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Furthermore, the predominant PE DHC lipids produced by these intestinal organisms were usually the LM PE DHC form (see Figure 1 for lipid structures and Figure 2A for recovery of these lipids in intestinal and oral bacteria).
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DIC interacts with ∼500 kDa dynein heavy chain (DHC) to form the cytoplasmic dynein complex.
The phosphoglycerol DHC lipids present forms with an additional iso-15:0 FA in ester linkage to the hydroxyl group of the iso-17:0 3-OH) FA.
These include both low-mass and high-mass forms of phosphoglycerol DHC and phosphoethanolamine DHC lipids.
PG DHC lipids (both the HM and LM forms) can exist with three aliphatic chains (the substituted or "Sub" form) or can be de-esterified to a lipid class with 2 aliphatic chains (the unsubstituted or "Un" form) [1], [5].
PDHCs include both low mass (LM) and high mass (HM) forms of phosphoglycerol dihydroceramide (PG DHC) and phosphoethanolamine dihydroceramide (PE DHC) lipids.
Understanding how the observed structure is formed by dimers of the DHC and accessory chains will require higher resolution information.
For example, the PDHC lipid constituents produced by P. gingivalis are predominantly HM PE DHC lipids whereas T. forsythia produces primarily LM PG DHC forms.
Ultraviolet B radiation to the skin transforms 7-DHC to previtamin D3, which undergoes nonenzymatic isomerisation to form vitamin D3.
Direct support for this idea comes from real-time imaging and immunoelectron microscopy experiments [39], which show that gurken transcripts form large particles that contain cytoplasmic dynein heavy chain (DHC) and the motor cofactors Egalitarian (Egl) and Bicaudal D (BicD) upon injection into stage 7 9 oocytes.
Aggregated numbers of ILI cases were reported to the DHC instead of individual cases and it was confirmed by health staff at the DHC of Binh Luc that: ILI has no form for recording and reporting, so only aggregated numbers were recorded and reported to DHC while the A/H1N1/2009 investigation did use a form for data collection.
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