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Following this reasoning, the overestimation will be largest in a region totally devoid of target receptors.
Tau pathology can be quantified by reference tissue models without arterial blood sampling when reference tissue devoid of target binding sites is available.
If this suggestion is correct, the ligand-bound state of 14-3-3ζm 14-3-3ζm 14-3-3ζm lisited chymoreypstablesis toan its form devoid of target peptides/proteins.
Classical mobility shift affinity, shown in Fig. 6A, involves the separation of an aptamer in a background electrolyte devoid of target and then in background electrolyte with increasing concentrations of target.
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The two Hsp90 and Hsp70 proteins each have one isoform (IDs: 50519 and 92743) that is devoid of targeting signals and appears to be cytosolic.
Development of a generally applicable sensitive hybridization-based assay devoid of any target amplification for the detection and identification of (pathogenic) bacterial and viral species.
Furthermore, it is not necessary for the reference region to be devoid of the target biology, as the data can be quantified subsequently, and a region with the fastest kinetics could be used as the reference region.
The blank samples were devoid of any target compounds at levels > 5% of the levels in samples except for cis-chlordane and trans-chlordane.
The intrabodies, one with an endoplasmic reticulum (ER) targeting signal and one devoid of a targeting sequence, were assessed in cells harboring a doxycycline (Dox -regulated mutant human amyloiDox -regulatedotein Swedish mutant (humanwe) tramyloidtion unit for their abilities to precursorβ protein egreSwedish
On the other hand, AKR2A interaction specifically with OEPs appears to be mediated by the plastid targeting sequences since AKR2A does not bind in vitro to OEP7 or OEP64 that are devoid of their targeting signals [43] or in vivo either to OEP7 when the protein's targeting signal is sterically blocked by an N-terminal appended GFP moiety [38] (Figure S5a) or to OEP9 lacking its CTS (Figure S5c).
To investigate the basic bioactivity of scTRAIL fusion proteins without the influence of targeting domains, we analyzed cell death induction on the target-negative cell lines HepG2 (hepatoma) and Jurkat (T-cell leukemia) and compared it with scTRAIL devoid of a targeting domain (Table 1 and Figure 3a).
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