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The phenotype observed when REST-null ES cells were differentiated on poly-D-lysine was similar to that observed with gelatine; few Sox+/Nestin+ NSCs developed and all neurons observed looked ailing, being rounded and devoid of processes (compare Fig. S8A with Fig. 3C and Fig. S8B with Fig. 3H and 3M).
That said, raw chocolate is devoid of the processed stuff I'm trying to avoid, so I assume it's not terrible.
Of course, the world today doesn't need one more fully automated, devoid-of-humanity process.
Even semi vegetarian diets are usually devoid of red and processed meats.
It is a property of the knower and devoid of actual process.
Also, our recordings were performed in isolated cells that were entirely devoid of dendritic processes.
Furthermore, neurons derived from REST-null ES cells are devoid of elaborate processes, have defects in migration and undergo increased cell death.
Collectively, these images demonstrated that whereas microglia are tightly packed and cover the tissue uniformly in young mice, coverage is impaired in old mice and more severely in 9-month-old APPSw,Ind Tg mice, leaving tissue space devoid of microglia processes (Fig. 4A).
Control tubes, devoid of enzyme, were also processed in parallel.
In the hemisphere shown in Figure 5, several contiguous zones encompassing ∼50% of the cortex are devoid of AP-labeled processes, and in the contralateral hemisphere of this brain ∼80% of the cortex is devoid of AP label (data not shown).
Background levels were calculated for each image stack as the average mean intensity value of several larger distributed areas devoid of any cellular processes (i.e., signal).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com