Serum IgG levels were determined by ELISA against three MSP4 baculovirus-encoded recombinant protein constructs, namely the full-length MSP4p40, MSP4p30 devoid of a highly polymorphic sequence stretch and the conserved C-terminal EGF-containing MSP4p20, as well as against a merozoite crude extract.
DH-DhL epimers which are devoid of the highly reactive α-methylene- γ-lactone moiety failed to show any significant antipseudomonalactivity at similar concentration to DhL (0.24 mg/mL).
This raises prospects for using P. cinnabarinus to produce pharmaceutical proteins, as the glycostructures (N- and O-chains) have a mammalian-like structure and are devoid of the highly antigenic galactofuranose residues found in expression hosts such as A. niger see [ 109] for review.
We report nuclear envelope remnants are relatively fluid membranes rich in sterols, devoid of sphingomyelin, and highly enriched in polyphosphoinositides and polyunsaturated phospholipids.
Unlike the strongly calcified exocuticle of the dactylus base, the claw exocuticle is devoid of mineral and is highly brominated.
We identified a promising pyrazolo[1,5- a]pyrimidine compound devoid of ABC transporter interaction, highly suitable for further preclinical and clinical evaluation for the treatment of cancer.
Monahan's handwriting is legible and straightforward, devoid of frills, much like the highly respected trainer himself.
This reaction is typically carried out in an atmosphere devoid of moisture to prevent the highly reactive PCl5 or POCl3 from reacting with atmospheric water [8] [11].
Furthermore, ESCs that lack all three methyltransferases (and are devoid of virtually all methylation) are highly resistant to differentiation, spontaneously reverting to pluripotency (Schmidt et al., 2012).
In respect to the studied acetylation (i) active loci marked by Pol II, H3K4me3, and devoid of strong H3K27me3 signals are highly enriched in H3K9ac and H3K14ac, (ii) bivalent loci, which are marked by H3K4me3, H3K27me3 and low Pol II signals contain both H3K9ac and H3K14ac signals, and (iii) inactive loci, on which either of the above signals is missing.
