The fact that the baseline values of diastolic blood pressure and heart rate remained without significant changes after prazosin, rauwolscine, the combination prazosin plus rauwolscine or propranolol (not shown), as previously reported [3], may be due to the fact that pithed rats are devoid of central and peripheral nervous influences.
In contrast, cells lacking pUL135 (RAd-Ctrl/MerlinΔUL135/Mock) displayed progressive loss of central actin as LatA concentrations increased until, at high concentrations, they resembled pUL135-expressing cells; i.e., a rounded cell devoid of central actin fibers.
The idea behind this experiments is that the tertiary structure of the crescent scaffold is likely to be similar for the EndoA and Amph N-BAR domain [9], [11], whereas the Amph-BAR is devoid of the central helix-loop appendage present in the EndoA-BAR.
This is an experimental model predictive of systemic (cardio vascular side effects [11, 12]; since this model is devoid of a functional central nervous system (see General methods below), one can categorically exclude the compensatory baroreflex mechanisms typically observed in intact or anaesthetized animals.
Their cytokeratin network develops to form a cage that partitions the intracellular space in two areas: a cortical one completely devoid of organelles and a central one in which are concentrated mainly all the organelles including the nucleus and all the autophagic vacuoles.
But they are not always effective because many tumors contain central zones devoid of blood and oxygen.
Clusters developed subsequently into alveolar-like cysts (ALCs), each comprising a central lumen devoid of cells enclosed completely by a monolayer of cells.
To quantify the retinogeniculate projections in the dLGN contralateral to the remaining eye, we first measured the size of the "gap" [10], [27], [28], which is the region devoid of CTB labeling in the central dLGN (Figure 1A. For the detailed definition of the gap, see Materials and Methods).
These divisions consist of the anterior fibromuscular stroma that is devoid of glandular tissue, transition zone, central zone, periurethral zone, and peripheral zone.
We found that the apical organ develops in a small central territory devoid of six3 expression, that instead expresses a number of other factors, many of which are found in the same location in other neuralians.
The majority of organic matter available to twilight zone residents therefore consists of refractory organic particles that are devoid of compounds thought to be central to life in these waters.
