In the normal dog coronary system Cx37 and Cx40 were only expressed in ECs while during collateral growth SMCs, normally devoid of a junctional system, strongly express Cx37 [ 19].
However farfetched its application to biological systems may appear to some (see, for example, [ 210- 212]), the hypothesis of a primeval role of metabolism originally devoid of a coding system in the emergence of the first precursors of living cells is gaining ground [ 213, 214].
Other efforts to create a network computer devoid of an operating system have failed in the past.
Civilian rule had fragmented, and a return to full civilian control would first require the establishment of local democracy hearkening back to Ayub Khan's "basic democracies"—a system devoid of competitive political parties.
Invertebrates are devoid of an adaptive immune system and they exclusively rely on innate immune reactions for theirs defense [1], [2].
This is an experimental model predictive of systemic (cardio vascular side effects [11, 12]; since this model is devoid of a functional central nervous system (see General methods below), one can categorically exclude the compensatory baroreflex mechanisms typically observed in intact or anaesthetized animals.
These mice are suggested to fall into three modes: FADD domain-negative mice, FADD−/− chimeras in a background devoid of immune system (FADD−/−→RAG-1−/−) and T-cell-specific FADD knockout mice.
It has been shown that PME elicits its anti-immobility effect via the 5-HT pathway devoid of the noradrenergic system.
Therefore, in the present work, we investigated the feasibility of blocking interconversion of PEP and PYR in strains devoid of the PTS system and with additional deletions in the pykA, pykF, and ppsA genes.
Conversely, we have recently observed that the adaptive immune system may promote bladder carcinoma progression in a mouse model of carcinogen-induced bladder carcinoma, since Rag2 −/− mice devoid of adaptive immune system developed less advanced tumours than immunocompetent hosts (Sugano et al, 2011).
