Further support for this idea comes from a recently devised protocol in which the differentiation of human ES cells toward cardiomyocyte lineages is greatly enhanced as compared to untreated human ES cells.
The devised protocol includes steps promoting effective preservation of embryo integrity, while allowing efficient penetration of the probes and an excellent signal-to-noise ratio.
In order to assess the impact of fatiguing exercise on SICI, a paired-pulse paradigm was used according to a previously devised protocol (Vucic et al. 2006).
Initiatives such as the concordat to support research integrity, which aim to agree principles across the sector, may help institutions devise protocols.
"Policy makers have historically considered the needs of witnesses in devising protocols" for execution, said Dr. Mark Dershwitz, a professor of anesthesiology at the University of Massachusetts who has testified about the drugs used in lethal injection.
We discuss how perturbations, like an infection with foreign antigen, a change in the influx of new idiotypes, or the random removal of idiotypes, may lead to autoreactivity and devise protocols which cause a reconstitution of the self-tolerant state.
While modelling the early steps of embryonic development in vitro may provide the best approach for generating differentiated cells with native properties, devising protocols for differentiation of pluripotent stem cells is largely an empirical task.
The literature demonstrates that it is possible to devise protocols which adjust the infusion rates of citrate and/or bicarbonate-containing solutions so as to avoid acid base disturbances at the same time as achieving long filter lives [ 6, 11, 15– 15].
Investigations were carried out by means of a dynamic shear rheometer and by employing specifically devised testing protocols.
We have expressed the active kinase domains for both JAK2 and JAK3 and devised purification protocols to resolve the non-, mono- (Y1007) and diphosphorylated (Y1007 and Y1008) states of JAK2 and non- and monophosphorylated states of JAK3 (Y980).
