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The 'half angel/half devil' role of NK cells during severe infection is also described.
Conversely, in its "devil" role, high miR-125b expression levels confer to breast cancer cells resistance to paclitaxel by targeting BAK1 [ 73] and are detected in miRNA signatures present in Tam- or fulvestrant-resistant breast cancer cell lines [ 17, 18].
In its "devil" role (associated with tumorigenesis), and in accordance with our study, overexpression of miR-205 has been shown to lead to a coordinated activation of the AKT signaling pathway in several cancer contexts [ 66- 69]; to our knowledge, though, it has never been shown in breast cancer cells.
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Two of three soloists on Saturday night – Susan Graham and John Relyea (who's doing quite a line in devil roles for Lepage these days) – proved themselves well able to emote convincingly, as well as sing beautifully, in their roles.
Even the Stranger, one of those devil roles that seem like foolproof show-stealers for a performer who can ham it up, didn't come off; Sam McKelton moved through it with curious restraint, and didn't seem to be having very much fun.
On a night when their snipers failed to score, the Devils' role players, including two rookies, left the defending Stanley Cup champions facing elimination.
It is a drastic departure from the Devils' usual role of boring everyone to tears while winning every game, 1-0.
Chambers and Katz are making the initial payments because of the Devils' important role in building the Newark arena -- and because the YankeeNets raised their debt load by $200 million last week with a sale of junk bonds.
For one, when people are assigned to play the devil's advocate role, they don't argue forcefully enough.
Designate one of your team members to play the devil's advocate role at each meeting.
You: My last boss would say that I supported her both by helping to carry out her agenda and also by playing the devil's advocate role to anticipate issues she might not have thought of otherwise.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com